Metabolic physiopathology

Publications (419)

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Muntane, Gerard; Janue, Anna; Fernandez, Nuria; Odena, Maria Antonia; Oliveira, Eliandre; Boluda, Susana; Portero-Otin, Manuel; Naudi, Alba; Boada, Jordi; Pamplona, Reinald; Ferrer, Isidre

Modification of brain lipids but not phenotype in alpha-synucleinopathy transgenic mice by long-term dietary n-3 fatty acids.

NEUROCHEMISTRY INTERNATIONAL 56 318-328. .

[doi:10.1016/j.neuint.2009.10.015]

Terni, Beatrice; Boada, Jordi; Portero-Otin, Manuel; Pamplona, Reinald; Ferrer, Isidro

Mitochondrial ATP-synthase in the entorhinal cortex is a target of oxidative stress at stages I/II of Alzheimer's disease pathology.

BRAIN PATHOLOGY 20 222-233. .

[doi:10.1111/j.1750-3639.2009.00266.x]

Fernandez, Liana Lisboa; Carmona, Marga; Portero-Otin, Manuel; Naudi, Alba; Pamplona, Reinald; Schroeder, Nadja; Ferrer, Isidro

Effects of increased iron intake during the neonatal period on the brain of adult AbetaPP/PS1 transgenic mice.

JOURNAL OF ALZHEIMERS DISEASE 19 1069-1080. .

[doi:10.3233/JAD-2010-1304]

Kichev, Anton; Ilieva, Ekaterina V.; Pinol-Ripoll, Gerard; Podlesniy, Petar; Ferrer, Isidro; Portero-Otin, Manuel; Pamplona, Reinald; Espinet, Carme

Cell death and learning impairment in mice caused by in vitro modified pro-NGF can be related to its increased oxidative modifications in Alzheimer disease.

AMERICAN JOURNAL OF PATHOLOGY 175 2574-2585. .

[doi:10.2353/ajpath.2009.090018]

Caro, Pilar; Gomez, Jose; Sanchez, Ines; Naudi, Alba; Ayala, Victoria; Lopez-Torres, Monica; Pamplona, Reinald; Barja, Gustavo

Forty percent methionine restriction decreases mitochondrial oxygen radical production and leak at complex I during forward electron flow and lowers oxidative damage to proteins and mitochondrial DNA in rat kidney and brain mitochondria.

REJUVENATION RESEARCH 12 421-434. .

[doi:10.1089/rej.2009.0902]

Negre-Salvayre, Anne; Salvayre, Robert; Auge, Nathalie; Pamplona, Reinald; Portero-Otin, Manuel

Hyperglycemia and glycation in diabetic complications.

ANTIOXIDANTS & REDOX SIGNALING 11 3071-3109. .

[doi:10.1089/ars.2009.2484]

Serrano, Jose; Jove, Mariona; Boada, Jordi; Josep Bellmunt, Maria; Pamplona, Reinald; Portero-Otin, Manuel

Dietary antioxidants interfere with Amplex Red-coupled-fluorescence assays.

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS 388 443-449. .

[doi:10.1016/j.bbrc.2009.08.041]

Erauskin, JL; Fourcade, S; Ferrer, I; Pamplona, R; Portero-Otin, M; Pujol, A

ANTIOXIDANTS AS A THERAPEUTIC HOPE FOR X-LINKED ADRENOLEUKODYSTROPHY

GLIA 57 100-101. .

Caro, Pilar; Gomez, Jose; Sanchez, Ines; Garcia, Ruben; Lopez-Torres, Monica; Naudi, Alba; Portero-Otin, Manuel; Pamplona, Reinald; Barja, Gustavo

Effect of 40% restriction of dietary amino acids (except methionine) on mitochondrial oxidative stress and biogenesis, AIF and SIRT1 in rat liver.

Biogerontology 10 579-592. .

[doi:10.1007/s10522-008-9200-4]

Brunet, Nuria; Tarabal, Olga; Esquerda, Josep E.; Caldero, Jordi

Excitotoxic motoneuron degeneration induced by glutamate receptor agonists and mitochondrial toxins in organotypic cultures of chick embryo spinal cord.

JOURNAL OF COMPARATIVE NEUROLOGY 516 277-290. .

[doi:10.1002/cne.22118]

Caldero, Jordi; Brunet, Nuria; Ciutat, Dolors; Hereu, Marta; Esquerda, Josep E.

Development of microglia in the chick embryo spinal cord: implications in the regulation of motoneuronal survival and death.

Journal Of Neuroscience Research 87 2447-2466. .

[doi:10.1002/jnr.22084]

Pamplona R

Restricción calórica y envejecimiento en humanos.

Revista espanola de geriatria y gerontologia 44 225-230. .

[doi:10.1016/j.regg.2009.04.002]